Plasma metabolic differences in cows affected by inactive ovaries or normal ovarian function post partum

Anestrus is essential to an unsuccessful pregnancy in dairy cows. One of the many factors that influences anestrus inactive ovary. To characterize detail plasma metabolic pro- file, cows suffering from ovaries were compared with those natural estrus. The Holstein 60 90 day postpartum intensive farm assigned into groups (IO, n=20) and estrus group (CON, n=22) according signs rectal palpation ovaries. Plasma samples two collected tail vein screen differential metabolites using gas chromatography/mass spectrometry (GC/MS) techniques multivariate statistical analysis pathways. results showed 106 compounds screened by GC/MS 14 IO decreased analyzing important variables projection values p MSA.Through pathway analysis, compounds, mainly associated carbohydrate metabolism amino acid meta- bolism, identified IO, which may seriously affect follicular growth. Metabolo- mics profiling, together MSA growth development related a single or multiple pathway(s).